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My research at UCLA focused on detecting and quantifying diseases such as cancer- at the sub-cellular, cellular and tissue levels. I employed various correlative nanoscale techniques to understand the anomalies in biophysical-bimolecular characteristics of individual vesicles and cells, and their molecular underpinnings, for biomarker discovery. Ultimately, the goal is to achieve reliable liquid biopsy-based diagnosis and treatment monitoring for cancers in a drop of blood, urine, or saliva.
RESEARCH INTERESTS
Exosomes and Extracellular Vesicles
as BIOfunctional NANOparticles
Nanomechanical profiling of single cells and tumor microenvironments
for cancer biomarker discovery
EDUCATION
Indian Institute of Technology, Delhi
PhD Biomedical Engineering
Certification
Clinical Translational Science Institute, UCLA
EV STRUCTURE
EV STRUCTURE-MECHANICS-FUNCTION
Field Emission Scanning Probe Microscopy image of saliva exosomes.
Sharma et al. ACS Nano
MECHANOBIOLOGY
OF CANCER CELLS & TISSUES
Super resolution STED Microscopy image of
ovarian cancer cell
Sharma et al. Nanomedicine
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